Recent Changes

Wednesday, November 21

  1. 12:38 pm
  2. 12:38 pm
  3. page Home edited ... Since 2007, our international research team has been working on a Canadian Institutes of Healt…
    ...
    Since 2007, our international research team has been working on a Canadian Institutes of Health Research funded project to study the ethical challenges in cluster randomized trials (CRTs). The ultimate goal of our project was to produce international consensus guidelines for the ethical conduct and ethics review of CRTs. The project comprised three components: an in-depth ethical analysis leading to a series of normative articles discussing the ethical issues in CRTs; review of the reporting of ethical issues in published CRTs; and surveys of CRT trialists and ethics review committee chairs. We have created this Wiki webpage to facilitate an open discussion about the ideas expressed in the series of articles and the proposed ethics guidelines. For further information about our project, please see our published study protocol.
    UPDATE: We are please to announce that the consensus guidelines have now been published in Plos Medicine!
    Link to article:
    http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001346

    Pdf file of final consensus statement:
    {Plos Med Consensus statement.pdf}
    (view changes)
    12:37 pm
  4. page Home edited ... Welcome to the Ethical Issues in Cluster Randomized Trials Wiki! Since 2007, our internationa…
    ...
    Welcome to the Ethical Issues in Cluster Randomized Trials Wiki!
    Since 2007, our international research team has been working on a Canadian Institutes of Health Research funded project to study the ethical challenges in cluster randomized trials (CRTs). The ultimate goal of our project was to produce international consensus guidelines for the ethical conduct and ethics review of CRTs. The project comprised three components: an in-depth ethical analysis leading to a series of normative articles discussing the ethical issues in CRTs; review of the reporting of ethical issues in published CRTs; and surveys of CRT trialists and ethics review committee chairs. We have created this Wiki webpage to facilitate an open discussion about the ideas expressed in the series of articles and the proposed ethics guidelines. For further information about our project, please see our published study protocol.
    ...
    in Plos Medicine.Medicine!
    Pdf file of final consensus statement:
    {Plos Med Consensus statement.pdf}

    Series of normative articles:
    1. Ethical Issues posed by cluster randomized trials in health research
    (view changes)
    12:36 pm
  5. page Home edited Welcome to the Ethical Issues in Cluster Randomized Trials Wiki! ... our project is was to …

    Welcome to the Ethical Issues in Cluster Randomized Trials Wiki!
    ...
    our project iswas to produce
    ...
    study protocol.
    UPDATE: We are please to announce that the consensus guidelines have now been published in Plos Medicine.

    Series of normative articles:
    1. Ethical Issues posed by cluster randomized trials in health research
    (view changes)
    12:34 pm
  6. page Home edited Welcome to the Ethical Issues in Cluster Randomized Trials Wiki! Over the past four years, Sin…

    Welcome to the Ethical Issues in Cluster Randomized Trials Wiki!
    Over the past four years,Since 2007, our international
    Series of normative articles:
    1. Ethical Issues posed by cluster randomized trials in health research
    (view changes)
    12:31 pm

Friday, September 14

  1. page 6. Gatekeepers in CRTs edited The role of gatekeepers in cluster randomized trials You may access the published Trials arti…

    The role of gatekeepers in cluster randomized trials
    You may access the published Trials article at this link:
    What is the role and authority of gatekeepers in CRTs?
    or you may download a pdf version here:

    {The role of gatekeepers in CRTs Trials 2012.pdf}
    (view changes)
    7:58 am
  2. page Home edited ... 4. Does clinical equipoise apply to cluster randomized trials in health research? 5. Assessin…
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    4. Does clinical equipoise apply to cluster randomized trials in health research?
    5. Assessing benefits and harms in cluster randomized trials (In preparation)
    6. TheWhat is the role and authority of gatekeepers
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    cluster randomized trialstrials?
    7. Cluster randomized trials in vunerable populations (In preparation)
    International consensus conference:
    (view changes)
    7:55 am
  3. page Home edited ... 3. When, and from whom, is informed consent required in cluster randomized trials? 4. Does cl…
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    3. When, and from whom, is informed consent required in cluster randomized trials?
    4. Does clinical equipoise apply to cluster randomized trials in health research?
    ...
    randomized trials (Not yet available)(In preparation)
    6. The
    ...
    randomized trials (Under review)
    7. Cluster
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    vunerable populations (Not yet available)(In preparation)
    International consensus conference:
    To develop ethics guidelines from this process, we held an international consensus conference in Ottawa, Ontario from 28-30 November, 2011. The first day of the conference was an open session on the ethics of CRTs (with simultaneous webcast), attended by invited representatives from funding agencies, regulators, research ethics committees, ethicists, journal editors and investigators. The results of the empirical studies and analyses of the six issues were presented and commented on by expert discussants and the audience. Attendees of the meeting included members of a multi-disciplinary Expert Panel, who subsequently met together in closed session for one and a half days to discuss identified issues and to develop guidelines. The Expert Panel is composed of external members — ethicists, researchers (cluster trialists, statisticians), policy makers and journal editors and four of the members of the research team.
    (view changes)
    7:54 am

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